SASInstitute A00-282 : Clinical Trials Programming Using SAS 9.4

A00-282 real exams

Exam Code: A00-282

Exam Name: Clinical Trials Programming Using SAS 9.4

Updated: Aug 26, 2026

Q & A: 144 Questions and Answers

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SASInstitute A00-282 Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Regulatory Submissions5%- ICH and FDA guidelines
- Compliance for clinical data reporting
Topic 2: Apply Statistical Procedures for Clinical Trials15%- PROC MEANS, FREQ, TABULATE
- Basic statistical analysis for clinical data
Topic 3: Clinical Trials Process5%- Derive programming requirements from protocol and CRF
- Clinical trial lifecycle and protocol
Topic 4: Transform or Summarize Clinical Trials Data15%- Aggregation and transposition
- Data step manipulation
- Derive variables and study days
Topic 5: Report Clinical Trials Results10%- Produce tables, listings, and figures
- PROC REPORT and PROC PRINT
Topic 6: Macro Programming for Clinical Trials15%- Create and call macros
- Macro variables and parameters
- Debugging macros
Topic 7: Validate Clinical Trial Data Reporting20%- Validation principles
- Use PROC COMPARE and log review
- Programming validation techniques
Topic 8: Manage Clinical Trials Data5%- Clean, merge, and subset data
- Access and explore clinical datasets
- Use SQL and dictionary tables
Topic 9: Clinical Trials Data Structures10%- Define.xml and dataset specifications
- CDISC standards: SDTM, ADaM
- Clinical domain structures

SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

1. The PROC SGPLOT step below needs to be modified to format the values on the horizontal axis.
proc sgplot data = work.adlb;
histogram AVAL;
<insert code here>
run;
Which statement CANNOT be used to format the values due to a syntax error?

A) format AVAL 8.2;
B) format AVAL comma8.2;
C) xaxis valuesformat = 8.2;
D) xaxis valuesformat = comma8.2;


2. What is the definition for treatment-emergent adverse event (TEAE)?

A) AE that continued after the first dose of study drug
B) AE that started or worsened after the first dose of study drug
C) AE that improved after the first dose of study drug
D) AE that started 6 months after the last dose of study drug


3. You have been asked to import an Excel spreadsheet.
What will lead to substantial differences between the original Excel spreadsheet and the resulting SAS data set?

A) the number of rows to be read from the Excel file
B) multiple value types within a single row
C) the number of columns to be read from the Excel file
D) multiple value types within a single column


4. The print below shows the first four observations from the TEST2 dataset.
Variable names are given in the first row.

The statistical analysis plan (SAP) requests that a two sample t-test be performed to compare the mean of variable FINALBP for levels of the variable TRT.
You review the following code from a colleague:
proc ttest data=test2;
by trt;
var finalbp;
run;
This code does not produce the analysis requested by the SAP.
What is wrong with this code?

A) Variable FINALBP should be specified on a TWOSAMP statement instead of a VAR statement.
B) Variable TRT should be specified on a WEIGHT statement instead of a BY statement.
C) Variable FINALBP should be specified on a TEST statement instead of a VAR statement.
D) Variable TRT should be specified on a CLASS statement instead of a BY statement.


5. This question will ask you to provide a line of missing code.
Given the following demography (DM) data set sorted by site with character variables SUBJID, SITE, SEX, RACE and numeric variables ENROLLDAT and DOB:

The following SAS program is submitted:
%macro p_demog(bylist, varlist, statlist=);
proc sort data=derived.dm out=dm;
by &bylist;
proc means data=dm;
by &bylist;
var &varlist;
output out=stats &statlist;
run;
%mend p_demog;
Which call to the p_demog macro provides only the MEAN of AGE by SEX into the output dataset STATS?

A) %p_demog(statlist=%str(mean=mymeanvar), sex, varlist=age)
B) %p_demog(sex, age, statlist=%str(mean=mymeanvar))
C) %p_demog(statlist=%str(mean=mymeanvar), sex, age)
D) %p_demog(sex age statlist=%str(mean=mymeanvar))


Solutions:

Question # 1
Answer: C
Question # 2
Answer: B
Question # 3
Answer: D
Question # 4
Answer: D
Question # 5
Answer: B

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